Benzeneacetic acid, α,α-dimethyl-4-(trifluoromethoxy)- - Names and Identifiers
Benzeneacetic acid, α,α-dimethyl-4-(trifluoromethoxy)- - Physico-chemical Properties
| Density | 1.298±0.06 g/cm3(Predicted) |
| Boling Point | 282.0±40.0 °C(Predicted) |
| pKa | 4.20±0.10(Predicted) |
Benzeneacetic acid, α,α-dimethyl-4-(trifluoromethoxy)- - Introduction
2-methyl-2-[4-(trifluoromethoxy)phenyl]propanoic acid is an organic compound with the chemical formula C12H11F3O3. It is a solid powder, colorless or yellowish.
The compound is commonly used in the pharmaceutical field as an intermediate for non-steroidal anti-inflammatory drugs. For example, it can be used to synthesize Nimesulide and other drugs containing a phenol structure. These drugs are often used to relieve pain, inflammation and fever.
The method of preparing 2-methyl-2-[4-(trifluoromethoxy)phenyl]propanoic acid is usually through p-dimethacrylic acid and p-trifluoromethoxyaniline (p-Trifluoromethoxyaniline) the reaction is carried out to obtain the target product.
Regarding safety information, this compound is relatively stable under normal use conditions, but it still needs to be handled with caution. It is irritating and may cause irritation to the eyes, skin and respiratory system. Therefore, wear protective gloves, goggles, and face shields to ensure adequate ventilation when exposed to this compound. At the same time, it is also toxic to the environment and water bodies, so waste should be handled and disposed of correctly. Relevant safety procedures and precautions should be followed when using or handling the compound.
Last Update：2024-04-09 21:11:58